Some useful links to MPN information resources, guidelines and detailed research articles are provided below.
SUMMARY OF TOPICS
Guidelines and general articles
Pediatric and Young Adult MPNs
Blood tests, bone marrow biopsies and MPN morphology
DISEASE SPECIFIC ARTICLES
Essential thrombocythemia (ET) specific information
Polycythemia Vera (PV) specific information
Myelofibrosis (MF) specific information
Myelofibrosis Stem Cell Transplant information
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Guidelines and general articles
- International review series on MPNs, Haematologica, April 2025
- Australian Optimal Care Pathways for Myeloproliferative Neoplasms, May 2024
- US National Comprehensive Cancer Network (NCCN) Guidelines for Patients: Myeloproliferative Neoplasms – 2024
- Myeloproliferative neoplasms: Classifications and an approach to diagnosis, Australian Journal of General Practice, 2021
- Biology and therapeutic targeting of molecular mechanisms in MPNs, Blood, 2023
- International Consensus Classification of Myeloid Neoplasms and Acute Leukemias: integrating morphologic, clinical, and genomic data, Blood, 2022
- Panel-based gene testing in myelodysplastic/myeloproliferative neoplasm overlap syndromes: Australasian Leukaemia and Lymphoma Group (ALLG) consensus statement, Pathology, 2022
- Myeloproliferative neoplasms unclassifiable: how I manage – practical approaches for 2022 and beyond, BJH, 2022
- How I approach the treatment of thrombotic complications in patients with myeloproliferative neoplasms, Review Article, How I treat series, Blood, 2024
- Exploring the Molecular Aspects of Myeloproliferative Neoplasms Associated with Unusual Site Vein Thrombosis: Review of the Literature and Latest Insights, International Journal of Molecular Sciences, 2024
- Genomic classification and outcomes of young patients with polycythemia vera and essential thrombocythemia according to the presence of splanchnic vein thrombosis and its chronology, Annals of Hematology, 2024
- Distinct clinico-molecular arterial and venous thrombosis scores for myeloproliferative neoplasms risk stratification, Leukemia, 2023
- Arterial and Venous Thromboembolic Complications in 832 Patients with BCR-ABL-Negative Myeloproliferative Neoplasms, Hamostaseologie, 2023
- Splanchnic vein thrombosis: Contemporary diagnostic and therapeutic strategies, Critical review, AJH, 2023
- Splanchnic vein thrombosis – a national retrospective cohort study of MPN-SVT, courtesy of MPN Hub, 2022
- Myeloproliferative Neoplasms and Dementia Risk: A Population-Based Cohort Study, EJH, 2024
- Myeloproliferative neoplasms – blurring the lines between cancer and chronic inflammatory disorder, 2023
- New Perspectives of Interferon-alpha2 and Inflammation in Treating Philadelphia-negative Chronic Myeloproliferative Neoplasms, Hemasphere, 2021
- Myeloproliferative blood cancers as a human neuroinflammation model for development of Alzheimer’s disease: evidences and perspectives, Journal of Neuroinflammation, 2020
- Ocular Manifestations in Patients with Philadelphia-Negative Myeloproliferative Neoplasms , 2020
- Patients with myeloproliferative neoplasms and high levels of systemic inflammation develop age-related macular degeneration, 2021
- Age related macular degeneration and myeloproliferative neoplasms – a common pathway, published thesis, 2022
- Aspirin therapy is associated with a lower risk of pregnancy loss in both JAK2– and CALR-mutated essential thrombocythemia, (Research article) AJH, 2024
- Myeloproliferative neoplasms in the adolescent and young adult population: a comprehensive review of the literature, 2024
- Childbirth rates in women with myeloproliferative neoplasms, Leukemia, 2024
- Maternal and fetal risks in pregnancy with MPN: 2023. Courtesy of MPN Hub
- What are the key considerations in managing pregnancy in myeloproliferative neoplasms, Elisabetta Abruzzese – courtesy of MPN Hub, 2023
- Outcome of 129 Pregnancies in Polycythemia Vera Patients: A Report of the European LeukemiaNET, Hemasphere, Letter, 2023
- Pregnancy and childbirth outcomes in women with myeloproliferative neoplasms—a nationwide population-based study of 342 pregnancies in Sweden, 2022
- Best practice recommendations for the management of MPN in pregnant patients, courtesy of MPN Hub, 2021
(Please note that these are not Australian guidelines and local Australian practices may differ.) - Myeloproliferative neoplasms and pregnancy: Overview and practice recommendations, AJH, 2020
- How we manage Philadelphia-negative myeloproliferative neoplasms in pregnancy, BJH 2020
Pediatric and Young Adult MPNs
- Myeloproliferative neoplasms in the adolescent and young adult population: a comprehensive review of the literature, 2024
- Myeloproliferative neoplasms: young patients, current data and future considerations, Annals of Hematology, 2024
- Weill Cornell Medicine Pediatric Myeloproliferative Neoplasm Program
- Characterization of myeloproliferative neoplasms in the paediatric and young adult population, BJH 2023
- Clinical features associated with thrombotic events in children with myeloproliferative neoplasms 2022
- Real-world study of children and young adults with myeloproliferative neoplasms: identifying risks and unmet needs, Blood Advances, 2022
- FACT SHEETS are provided on all the main treatments available for Australian MPN patients. These are available in several languages.
- Articles on MPN treatment – this link includes:
– a conversation with an MPN specialist about how interferons work in MPN patients,
– comparison studies of interferon and hydroxyurea,
– efficacy and safety of myelofibrosis treatments,
– clinical trial outcomes from Australia and overseas, and
– new developments for myelofibrosis treatments.
Blood tests, bone marrow biopsies and MPN morphology
- Understand your blood tests
- Variability of bone marrow biopsy reporting affects accuracy of diagnosis of myeloproliferative neoplasms: data from the ALLG MPN01 registry, Pathology Journal, RCPA, 2023
- Morphology of myeloproliferative neoplasms, Int J Lab Hematol. 2023
